Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7454.093 | 0.9286 | 0.8920 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7454.093 | 0.9619 | 0.9427 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7454.093 | 0.8718 | 0.8047 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7454.093 | 0.8537 | 0.7765 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7454.093 | 0.9696 | 0.9542 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7454.093 | 0.7079 | 0.5438 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7454.093 | 0.0164 | -0.9082 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7455.093 | 1.0285 | 1.0328 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7455.093 | 1.0045 | 1.0053 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7455.093 | 1.0268 | 1.0309 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7455.093 | 1.0898 | 1.1022 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7455.093 | 1.0540 | 1.0618 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7455.093 | 0.9819 | 0.9789 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7455.093 | 0.9521 | 0.9439 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7455.093 | 0.7038 | 0.6316 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7455.093 | 0.0858 | -0.5182 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10469.1 | 1.0548 | 1.0690 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10469.1 | 0.9929 | 0.9910 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10469.1 | 0.9920 | 0.9899 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10469.1 | 0.9319 | 0.9123 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10469.1 | 1.0181 | 1.0230 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10469.1 | 0.9367 | 0.9184 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10469.1 | 0.9255 | 0.9038 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10469.1 | 0.6537 | 0.5260 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10469.1 | 0.0094 | -0.8972 | 1.5717 |