Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7462.093 | 1.0203 | 1.0929 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7462.093 | 0.9613 | 0.8295 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7462.093 | 1.0376 | 1.1737 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7462.093 | 0.9815 | 0.9174 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7462.093 | 1.0049 | 1.0224 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7462.093 | 0.9744 | 0.8862 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7462.093 | 1.0371 | 1.1714 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7462.093 | 1.0464 | 1.2157 | 0.4426 | |
| HCC2185 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7462.093 | 0.7331 | -0.0083 | 0.4426 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 7465.1 | 0.9603 | 0.9367 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 7465.1 | 0.8658 | 0.7839 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 7465.1 | 0.9891 | 0.9827 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 7465.1 | 0.9510 | 0.9219 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 7465.1 | 0.9005 | 0.8404 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 7465.1 | 0.9272 | 0.8835 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 7465.1 | 0.9529 | 0.9250 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 7465.1 | 0.6939 | 0.4966 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 7465.1 | 0.4908 | 0.1370 | 1.2603 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7466.093 | 0.9939 | 0.9857 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7466.093 | 0.9680 | 0.9254 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7466.093 | 0.9814 | 0.9565 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7466.093 | 0.9845 | 0.9637 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7466.093 | 0.9817 | 0.9573 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7466.093 | 0.9800 | 0.9533 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7466.093 | 0.9556 | 0.8965 | 0.8543 |