Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7808.011 | 0.1731 | -0.0281 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7808.011 | 0.0005 | -0.9131 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7808.011 | 0.0005 | -0.9131 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9226.021 | 1.0336 | 1.0265 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9226.021 | 1.0209 | 1.0166 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9226.021 | 1.0666 | 1.0519 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9226.021 | 0.9317 | 0.9445 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9226.021 | 0.6280 | 0.6622 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9226.021 | 0.3499 | 0.3172 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9226.021 | 0.1398 | -0.0854 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9226.021 | 0.0079 | -0.7083 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9226.021 | 0.0058 | -0.7424 | 2.5142 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7810.011 | 1.1052 | 1.2287 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7810.011 | 1.0385 | 1.0834 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7810.011 | 1.0889 | 1.1930 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7810.011 | 1.0900 | 1.1955 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7810.011 | 1.0443 | 1.0961 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7810.011 | 0.9079 | 0.8015 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7810.011 | 0.6659 | 0.2881 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7810.011 | 0.1169 | -0.8040 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7810.011 | 0.0563 | -0.9111 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9233.12 | 1.1405 | 1.2435 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9233.12 | 0.9999 | 0.9998 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9233.12 | 1.0244 | 1.0425 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9233.12 | 1.0242 | 1.0422 | 1.1442 |