Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9233.12 | 1.0415 | 1.0723 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9233.12 | 0.9862 | 0.9759 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9233.12 | 0.7182 | 0.4976 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9233.12 | 0.1263 | -0.6722 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9233.12 | 0.0546 | -0.8425 | 1.1442 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7811.011 | 1.0572 | 1.2694 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7811.011 | 0.9011 | 0.5785 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7811.011 | 0.9744 | 0.8853 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7811.011 | 0.8803 | 0.4969 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7811.011 | 0.7582 | 0.0662 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7811.011 | 0.0892 | -0.9918 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7811.011 | 0.0195 | -0.9997 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7811.011 | 0.0203 | -0.9997 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7811.011 | 0.0083 | -1.0000 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7812.011 | 1.1131 | 1.2123 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7812.011 | 0.9793 | 0.9610 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7812.011 | 1.0441 | 1.0830 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7812.011 | 1.0685 | 1.1287 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7812.011 | 0.7681 | 0.5600 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7812.011 | 0.3596 | -0.2366 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7812.011 | 0.0650 | -0.8476 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7812.011 | 0.0541 | -0.8717 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7812.011 | 0.0050 | -0.9863 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9244.021 | 1.2328 | 2.1705 | 0.4542 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9244.021 | 1.0231 | 1.1032 | 0.4542 |