Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7515.093 | 0.9023 | 0.8550 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7515.093 | 0.8565 | 0.7855 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7515.093 | 0.6734 | 0.4973 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7515.093 | 0.5238 | 0.2457 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7515.093 | 0.0070 | -0.9470 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7516.093 | 1.0119 | 1.0180 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7516.093 | 0.9448 | 0.9155 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7516.093 | 0.9875 | 0.9810 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7516.093 | 0.9662 | 0.9484 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7516.093 | 0.9626 | 0.9428 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7516.093 | 1.0226 | 1.0344 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7516.093 | 0.6438 | 0.4309 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7516.093 | 0.4935 | 0.1688 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7516.093 | 0.1683 | -0.4844 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7517.093 | 0.9735 | 0.9642 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7517.093 | 1.0338 | 1.0453 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7517.093 | 0.9340 | 0.9102 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7517.093 | 0.9990 | 0.9986 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7517.093 | 0.9410 | 0.9199 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7517.093 | 0.9553 | 0.9395 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7517.093 | 0.7162 | 0.5979 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7517.093 | 0.4950 | 0.2463 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7517.093 | 0.2098 | -0.3003 | 1.4869 | |
| SK-BR-3 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7527.093 | 1.0032 | 1.0035 | 1.8070 | |
| SK-BR-3 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7527.093 | 0.9611 | 0.9566 | 1.8070 |