Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7443.066 | 0.9855 | 0.9692 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7443.066 | 1.0076 | 1.0162 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7443.066 | 0.9827 | 0.9633 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7443.066 | 1.0120 | 1.0255 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7443.066 | 0.9486 | 0.8910 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7443.066 | 0.9506 | 0.8952 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7443.066 | 0.9056 | 0.8001 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7443.066 | 0.2919 | -0.4593 | 0.9414 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7444.066 | 1.0636 | 1.1848 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7444.066 | 1.0913 | 1.2671 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7444.066 | 1.0744 | 1.2169 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7444.066 | 1.0293 | 1.0846 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7444.066 | 0.9585 | 0.8819 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7444.066 | 0.9587 | 0.8827 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7444.066 | 0.9445 | 0.8428 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7444.066 | 1.0349 | 1.1008 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7444.066 | 0.3274 | -0.5968 | 0.6972 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 10441.066 | 0.9734 | 0.9540 | 1.1591 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 10441.066 | 0.9741 | 0.9552 | 1.1591 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 10441.066 | 0.9390 | 0.8943 | 1.1591 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 10441.066 | 0.9393 | 0.8948 | 1.1591 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 10441.066 | 0.9277 | 0.8746 | 1.1591 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 10441.066 | 0.9602 | 0.9311 | 1.1591 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 10441.066 | 0.9029 | 0.8313 | 1.1591 | |
| HCC1428 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 10441.066 | 0.8978 | 0.8223 | 1.1591 |