Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.0213	uM	5896.066	0.9455	0.9227	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.107	uM	5896.066	0.9056	0.8653	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.533	uM	5896.066	0.7312	0.6048	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	2.67	uM	5896.066	0.5584	0.3278	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	13.3	uM	5896.066	0.6147	0.4206	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	66.7	uM	5896.066	0.0071	-0.9381	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000171	uM	5897.066	0.9897	0.9838	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000853	uM	5897.066	1.0027	1.0042	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.00427	uM	5897.066	0.9955	0.9929	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.0213	uM	5897.066	1.0149	1.0234	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.107	uM	5897.066	1.0285	1.0446	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.533	uM	5897.066	1.0032	1.0049	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	2.67	uM	5897.066	0.8977	0.8375	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	13.3	uM	5897.066	0.7186	0.5430	1.2737
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	66.7	uM	5897.066	0.0083	-0.9537	1.2737
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	5898.066	0.9134	0.7238	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.000853	uM	5898.066	0.9504	0.8398	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.00427	uM	5898.066	0.9732	0.9127	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.0213	uM	5898.066	0.9492	0.8362	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.107	uM	5898.066	0.9916	0.9725	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.533	uM	5898.066	0.9547	0.8537	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	2.67	uM	5898.066	0.9871	0.9578	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	13.3	uM	5898.066	0.9026	0.6904	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	66.7	uM	5898.066	0.6089	-0.1137	0.6097
600MPE	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	5899.066	0.9640	0.8986	0.7056

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)