Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7539.066 | 0.3653 | -0.1028 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7541.066 | 0.9457 | 0.9245 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7541.066 | 0.9673 | 0.9547 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7541.066 | 0.9627 | 0.9484 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7541.066 | 0.9795 | 0.9716 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7541.066 | 0.9885 | 0.9841 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7541.066 | 0.9246 | 0.8949 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7541.066 | 0.9200 | 0.8884 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7541.066 | 0.8353 | 0.7669 | 1.4520 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7541.066 | 0.1506 | -0.4570 | 1.4520 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7542.066 | 0.9506 | 0.9081 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7542.066 | 0.9525 | 0.9117 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7542.066 | 0.9422 | 0.8924 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7542.066 | 0.9586 | 0.9230 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7542.066 | 0.9785 | 0.9601 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7542.066 | 0.9553 | 0.9168 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7542.066 | 0.8902 | 0.7952 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7542.066 | 0.8501 | 0.7199 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7542.066 | 0.6153 | 0.2738 | 1.0766 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7543.066 | 0.9623 | 0.9493 | 1.4960 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7543.066 | 0.9483 | 0.9302 | 1.4960 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7543.066 | 0.9294 | 0.9045 | 1.4960 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7543.066 | 0.9029 | 0.8680 | 1.4960 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7543.066 | 0.9769 | 0.9689 | 1.4960 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7543.066 | 0.9293 | 0.9043 | 1.4960 |