Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7535.066 | 0.9525 | 0.8792 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7535.066 | 0.9158 | 0.7871 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7535.066 | 1.0175 | 1.0448 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7535.066 | 1.0192 | 1.0494 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7535.066 | 0.9581 | 0.8933 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7535.066 | 0.9134 | 0.7809 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7535.066 | 0.9289 | 0.8198 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7535.066 | 0.2238 | -0.7057 | 0.7812 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7537.066 | 0.9320 | 0.9326 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7537.066 | 0.9543 | 0.9549 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7537.066 | 0.9272 | 0.9278 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7537.066 | 0.9492 | 0.9499 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7537.066 | 0.9314 | 0.9320 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7537.066 | 0.9301 | 0.9307 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7537.066 | 0.9147 | 0.9150 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7537.066 | 0.7772 | 0.7691 | 2.0549 | |
| SUM229PE | TNBC | - | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7537.066 | 0.0275 | -0.6523 | 2.0549 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7539.066 | 0.8519 | 0.7605 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7539.066 | 0.9008 | 0.8405 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7539.066 | 0.8992 | 0.8378 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7539.066 | 0.9070 | 0.8505 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7539.066 | 0.6780 | 0.4679 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7539.066 | 0.8594 | 0.7728 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7539.066 | 0.8944 | 0.8300 | 1.2564 | |
| SUM52PE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7539.066 | 0.7704 | 0.6250 | 1.2564 |