Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9913.021 | 0.0365 | -0.9999 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10150.021 | 1.0645 | 1.2733 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10150.021 | 1.0222 | 1.0920 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10150.021 | 1.0915 | 1.3929 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10150.021 | 0.9281 | 0.7167 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10150.021 | 1.0293 | 1.1218 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10150.021 | 0.6498 | -0.1729 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10150.021 | 0.5220 | -0.4717 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10150.021 | 0.1649 | -0.9501 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10150.021 | 0.0150 | -0.9996 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10151.021 | 1.1349 | 2.0290 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10151.021 | 0.9587 | 0.7417 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10151.021 | 1.0772 | 1.5526 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10151.021 | 0.9185 | 0.5130 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10151.021 | 0.7683 | -0.1578 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10151.021 | 0.6908 | -0.4059 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10151.021 | 0.4834 | -0.8159 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10151.021 | 0.1785 | -0.9930 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10151.021 | 0.0248 | -1.0000 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10267.011 | 1.1880 | 2.2311 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10267.011 | 1.0430 | 1.2490 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10267.011 | 1.1576 | 2.0057 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10267.011 | 0.9370 | 0.6684 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10267.011 | 0.8707 | 0.3601 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10267.011 | 0.6972 | -0.2673 | 0.3592 |