Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 9033.075 | 1.0147 | 1.0308 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9033.075 | 0.9942 | 0.9879 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9033.075 | 0.9440 | 0.8831 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9033.075 | 0.9222 | 0.8376 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 9033.075 | 0.7520 | 0.4844 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9033.075 | 0.5226 | 0.0145 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9033.075 | 0.2800 | -0.4719 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9033.075 | 0.1348 | -0.7541 | 0.9560 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9897.021 | 1.0653 | 1.2183 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9897.021 | 0.9832 | 0.9452 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9897.021 | 1.0346 | 1.1146 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9897.021 | 1.0192 | 1.0632 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9897.021 | 0.8776 | 0.6147 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9897.021 | 0.6632 | 0.0204 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9897.021 | 0.4400 | -0.4791 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9897.021 | 0.2911 | -0.7352 | 0.6103 | |
| T47D | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9897.021 | 0.0730 | -0.9725 | 0.6103 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9913.021 | 1.1867 | 2.3084 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9913.021 | 1.0146 | 1.0871 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9913.021 | 1.1362 | 1.9110 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9913.021 | 0.9836 | 0.9049 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9913.021 | 0.8291 | 0.1526 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9913.021 | 0.7689 | -0.0765 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9913.021 | 0.5949 | -0.5657 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9913.021 | 0.1995 | -0.9825 | 0.3401 |