Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10753.152 | 0.9122 | 0.8701 | 1.3690 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10753.152 | 0.8500 | 0.7762 | 1.3690 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10753.152 | 0.0128 | -0.9169 | 1.3690 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10753.152 | 0.0113 | -0.9245 | 1.3690 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10753.152 | 0.0122 | -0.9202 | 1.3690 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12000.159 | 0.9348 | 0.8656 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12000.159 | 0.8999 | 0.7938 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12000.159 | 0.8913 | 0.7762 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12000.159 | 0.8809 | 0.7547 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12000.159 | 0.8648 | 0.7218 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12000.159 | 0.6300 | 0.2418 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12000.159 | 0.1459 | -0.7254 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12000.159 | 0.0080 | -0.9863 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 12000.159 | 0.0077 | -0.9868 | 0.9695 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12084.159 | 0.9407 | 0.9030 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12084.159 | 1.0115 | 1.0187 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12084.159 | 0.9692 | 0.9497 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12084.159 | 0.9855 | 0.9764 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12084.159 | 0.8070 | 0.6799 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12084.159 | 0.5747 | 0.2746 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12084.159 | 0.0054 | -0.9712 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12084.159 | 0.0042 | -0.9765 | 1.2294 | |
| HCC1395 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 12084.159 | 0.0018 | -0.9882 | 1.2294 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12001.159 | 0.9099 | 0.7513 | 0.7107 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12001.159 | 0.8972 | 0.7170 | 0.7107 |