Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Nelfinavir | 0.000427 | uM | 13107.174 | 0.9572 | 0.8741 | 0.6723 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 0.00213 | uM | 13107.174 | 0.9611 | 0.8853 | 0.6723 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 0.0107 | uM | 13107.174 | 0.9718 | 0.9167 | 0.6723 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 0.0533 | uM | 13107.174 | 0.9392 | 0.8218 | 0.6723 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 0.267 | uM | 13107.174 | 0.9388 | 0.8207 | 0.6723 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 1.33 | uM | 13107.174 | 0.9732 | 0.9209 | 0.6723 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 6.67 | uM | 13107.174 | 0.8326 | 0.5228 | 0.6723 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 33.3 | uM | 13107.174 | 0.5495 | -0.1791 | 0.6723 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 0.0000853 | uM | 13038.174 | 1.0014 | 1.0024 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 0.000427 | uM | 13038.174 | 0.9766 | 0.9610 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 0.00213 | uM | 13038.174 | 0.9998 | 0.9997 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 0.0107 | uM | 13038.174 | 1.1056 | 1.1742 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 0.0533 | uM | 13038.174 | 1.0201 | 1.0334 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 0.267 | uM | 13038.174 | 1.0030 | 1.0049 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 1.33 | uM | 13038.174 | 1.0052 | 1.0087 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 6.67 | uM | 13038.174 | 0.9771 | 0.9619 | 1.2027 | |||
| HCC1569 | HER2amp | Basal A | Nelfinavir | 33.3 | uM | 13038.174 | 0.9376 | 0.8956 | 1.2027 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 12702.174 | 0.9871 | 0.9860 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 12702.174 | 0.9319 | 0.9253 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 12702.174 | 0.9263 | 0.9189 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 12702.174 | 0.9646 | 0.9614 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 12702.174 | 0.9845 | 0.9832 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 12702.174 | 0.9491 | 0.9444 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 12702.174 | 1.0025 | 1.0027 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 12702.174 | 0.8209 | 0.7977 | 1.8506 |