Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 12696.174 | 0.9505 | 0.8451 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 12696.174 | 0.9602 | 0.8752 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 12696.174 | 0.9299 | 0.7820 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 12696.174 | 0.9505 | 0.8451 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 12696.174 | 0.7802 | 0.3488 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 12696.174 | 0.0160 | -0.9972 | 0.6299 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 0.0000853 | uM | 13538.174 | 1.0009 | 1.0038 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 0.000427 | uM | 13538.174 | 0.9866 | 0.9425 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 0.00213 | uM | 13538.174 | 0.9740 | 0.8888 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 0.0107 | uM | 13538.174 | 0.9993 | 0.9969 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 0.0533 | uM | 13538.174 | 1.0008 | 1.0036 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 0.267 | uM | 13538.174 | 0.9922 | 0.9665 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 1.33 | uM | 13538.174 | 0.9936 | 0.9722 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 6.67 | uM | 13538.174 | 0.9906 | 0.9595 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Nelfinavir | 33.3 | uM | 13538.174 | 0.8370 | 0.3603 | 0.4615 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 0.0000853 | uM | 12612.174 | 0.9704 | 0.9018 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 0.000427 | uM | 12612.174 | 0.9443 | 0.8168 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 0.00213 | uM | 12612.174 | 0.9971 | 0.9902 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 0.0107 | uM | 12612.174 | 0.9357 | 0.7890 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 0.0533 | uM | 12612.174 | 0.9725 | 0.9086 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 0.267 | uM | 12612.174 | 0.9503 | 0.8362 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 1.33 | uM | 12612.174 | 0.9038 | 0.6879 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 6.67 | uM | 12612.174 | 0.4336 | -0.5076 | 0.5962 | |||
| HCC1419 | HER2amp | Luminal | Nelfinavir | 33.3 | uM | 12612.174 | 0.0272 | -0.9953 | 0.5962 | |||
| HCC1428 | HR+ | Luminal | Nelfinavir | 0.0000853 | uM | 13107.174 | 0.9878 | 0.9638 | 0.6723 |