Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 12702.174 | 0.0076 | -0.8571 | 1.8506 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 13115.174 | 1.0107 | 1.0263 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 13115.174 | 0.9788 | 0.9478 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 13115.174 | 1.0349 | 1.0862 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 13115.174 | 0.9964 | 0.9912 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 13115.174 | 1.0333 | 1.0824 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 13115.174 | 0.9649 | 0.9139 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 13115.174 | 0.9802 | 0.9513 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 13115.174 | 0.8109 | 0.5450 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 13115.174 | 0.0036 | -0.9981 | 0.8122 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 0.0000853 | uM | 13546.174 | 0.9633 | 0.9388 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 0.000427 | uM | 13546.174 | 0.9285 | 0.8804 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 0.00213 | uM | 13546.174 | 0.9138 | 0.8557 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 0.0107 | uM | 13546.174 | 0.9823 | 0.9705 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 0.0533 | uM | 13546.174 | 1.0353 | 1.0586 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 0.267 | uM | 13546.174 | 0.9634 | 0.9389 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 1.33 | uM | 13546.174 | 0.9824 | 0.9708 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 6.67 | uM | 13546.174 | 0.9265 | 0.8771 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Nelfinavir | 33.3 | uM | 13546.174 | 0.6446 | 0.3886 | 1.2035 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 0.0000853 | uM | 13135.174 | 0.9482 | 0.8074 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 0.000427 | uM | 13135.174 | 0.9337 | 0.7553 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 0.00213 | uM | 13135.174 | 0.9324 | 0.7505 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 0.0107 | uM | 13135.174 | 0.9537 | 0.8276 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 0.0533 | uM | 13135.174 | 0.9510 | 0.8177 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 0.267 | uM | 13135.174 | 0.9265 | 0.7294 | 0.5256 |