Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Nelfinavir | 1.33 | uM | 13135.174 | 0.9266 | 0.7299 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 6.67 | uM | 13135.174 | 0.7734 | 0.2266 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Nelfinavir | 33.3 | uM | 13135.174 | 0.0756 | -0.9853 | 0.5256 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 12939.174 | 0.9946 | 0.9692 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 12939.174 | 0.9558 | 0.7552 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 12939.174 | 0.9621 | 0.7888 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 12939.174 | 1.0024 | 1.0140 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 12939.174 | 0.9612 | 0.7842 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 12939.174 | 0.9633 | 0.7953 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 12939.174 | 0.9222 | 0.5830 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 12939.174 | 0.8029 | 0.0616 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 12939.174 | 0.0546 | -0.9996 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 13583.174 | 1.0655 | 1.3793 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 13583.174 | 0.9781 | 0.8826 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 13583.174 | 1.0236 | 1.1319 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 13583.174 | 1.0030 | 1.0163 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 13583.174 | 1.0415 | 1.2353 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 13583.174 | 0.9904 | 0.9476 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 13583.174 | 1.0129 | 1.0716 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 13583.174 | 0.8645 | 0.3425 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 13583.174 | 0.0098 | -1.0000 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 13733.174 | 0.9495 | 0.8064 | 0.5093 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 13733.174 | 0.9575 | 0.8365 | 0.5093 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 13733.174 | 0.9323 | 0.7428 | 0.5093 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 13733.174 | 0.9710 | 0.8875 | 0.5093 |