Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Nelfinavir | 0.267 | uM | 12690.174 | 0.9841 | 0.9869 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 1.33 | uM | 12690.174 | 0.9747 | 0.9791 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 6.67 | uM | 12690.174 | 0.7939 | 0.8193 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 33.3 | uM | 12690.174 | 0.0009 | -0.8879 | 2.4378 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 0.0000853 | uM | 12647.174 | 0.9558 | 0.9058 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 0.000427 | uM | 12647.174 | 0.9447 | 0.8821 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 0.00213 | uM | 12647.174 | 0.9794 | 0.9561 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 0.0107 | uM | 12647.174 | 0.9435 | 0.8796 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 0.0533 | uM | 12647.174 | 0.8994 | 0.7859 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 0.267 | uM | 12647.174 | 0.7910 | 0.5569 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 1.33 | uM | 12647.174 | 0.8979 | 0.7827 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 6.67 | uM | 12647.174 | 0.6584 | 0.2797 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Nelfinavir | 33.3 | uM | 12647.174 | 0.0484 | -0.9213 | 0.9362 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 13099.174 | 1.0220 | 1.0465 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 13099.174 | 0.9701 | 0.9367 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 13099.174 | 0.9267 | 0.8450 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 13099.174 | 0.9752 | 0.9475 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 13099.174 | 0.9475 | 0.8889 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 13099.174 | 0.9773 | 0.9520 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 13099.174 | 0.9818 | 0.9615 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 13099.174 | 0.8482 | 0.6800 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 13099.174 | 0.1003 | -0.8248 | 0.9441 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 12696.174 | 0.9731 | 0.9151 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 12696.174 | 0.9177 | 0.7451 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 12696.174 | 0.9364 | 0.8018 | 0.6299 |