Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 13579.174 | 0.8002 | 0.5145 | 0.8018 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 13579.174 | 0.0081 | -0.9951 | 0.8018 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 0.0000853 | uM | 13125.174 | 0.9609 | 0.9192 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 0.000427 | uM | 13125.174 | 0.9127 | 0.8199 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 0.00213 | uM | 13125.174 | 0.9625 | 0.9226 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 0.0107 | uM | 13125.174 | 0.9802 | 0.9591 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 0.0533 | uM | 13125.174 | 0.9569 | 0.9111 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 0.267 | uM | 13125.174 | 0.9742 | 0.9466 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 1.33 | uM | 13125.174 | 0.9394 | 0.8751 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 6.67 | uM | 13125.174 | 0.9019 | 0.7978 | 0.9685 | |||
| BT-474 | HER2amp | Luminal | Nelfinavir | 33.3 | uM | 13125.174 | 0.1778 | -0.6639 | 0.9685 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 0.0000853 | uM | 13130.174 | 0.9763 | 0.9084 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 0.000427 | uM | 13130.174 | 0.9347 | 0.7530 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 0.00213 | uM | 13130.174 | 0.9735 | 0.8981 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 0.0107 | uM | 13130.174 | 0.9749 | 0.9031 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 0.0533 | uM | 13130.174 | 0.9743 | 0.9009 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 0.267 | uM | 13130.174 | 0.9661 | 0.8700 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 1.33 | uM | 13130.174 | 0.9403 | 0.7737 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 6.67 | uM | 13130.174 | 0.9160 | 0.6855 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Nelfinavir | 33.3 | uM | 13130.174 | 0.1909 | -0.9209 | 0.5126 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 0.0000853 | uM | 12690.174 | 0.9796 | 0.9832 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 0.000427 | uM | 12690.174 | 0.9976 | 0.9980 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 0.00213 | uM | 12690.174 | 1.0004 | 1.0003 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 0.0107 | uM | 12690.174 | 1.0331 | 1.0269 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Nelfinavir | 0.0533 | uM | 12690.174 | 1.0205 | 1.0167 | 2.4378 |