Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
ZR75B	HR+	Luminal	NU6102	CDK1/2	CDK	0.533	uM	11939.147	0.9856	0.9821	1.6102
ZR75B	HR+	Luminal	NU6102	CDK1/2	CDK	2.67	uM	11939.147	0.9642	0.9552	1.6102
ZR75B	HR+	Luminal	NU6102	CDK1/2	CDK	13.3	uM	11939.147	0.6936	0.5935	1.6102
ZR75B	HR+	Luminal	NU6102	CDK1/2	CDK	66.7	uM	11939.147	0.2088	-0.2441	1.6102
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000171	uM	5894.066	0.9652	0.9535	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000853	uM	5894.066	1.0364	1.0481	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.00427	uM	5894.066	1.0108	1.0143	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.0213	uM	5894.066	1.0324	1.0429	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.107	uM	5894.066	0.9910	0.9880	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.533	uM	5894.066	0.8110	0.7398	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	2.67	uM	5894.066	0.7021	0.5806	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	13.3	uM	5894.066	0.5453	0.3359	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	66.7	uM	5894.066	0.0120	-0.8949	1.5027
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000171	uM	5895.066	1.0368	1.0633	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000853	uM	5895.066	1.0346	1.0594	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.00427	uM	5895.066	1.0547	1.0939	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.0213	uM	5895.066	1.0425	1.0731	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.107	uM	5895.066	0.9813	0.9678	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	0.533	uM	5895.066	0.8774	0.7869	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	2.67	uM	5895.066	0.6798	0.4344	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	13.3	uM	5895.066	0.5085	0.1172	1.1612
184A1	NM	Basal	Nutlin 3a	MDM2	MDM2	66.7	uM	5895.066	0.0069	-0.9725	1.1612
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000171	uM	5896.066	0.9602	0.9438	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.000853	uM	5896.066	0.9765	0.9669	1.4224
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	0.00427	uM	5896.066	0.9483	0.9267	1.4224

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)