Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11938.147 | 0.9692 | 0.9097 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11938.147 | 0.0275 | -0.9901 | 0.6765 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11660.147 | 0.9283 | 0.8643 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11660.147 | 0.9286 | 0.8648 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11660.147 | 0.9551 | 0.9152 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11660.147 | 0.9252 | 0.8585 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11660.147 | 0.9366 | 0.8800 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11660.147 | 0.9397 | 0.8858 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11660.147 | 0.9262 | 0.8604 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11660.147 | 0.8445 | 0.7050 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11660.147 | 0.4307 | -0.0971 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12003.147 | 0.8456 | 0.7367 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12003.147 | 0.8933 | 0.8188 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12003.147 | 0.8615 | 0.7641 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12003.147 | 0.8664 | 0.7727 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12003.147 | 0.8880 | 0.8098 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12003.147 | 0.8525 | 0.7486 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12003.147 | 0.8707 | 0.7801 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12003.147 | 0.6033 | 0.3072 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12003.147 | 0.1580 | -0.5767 | 1.1884 | |
| ZR75B | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11939.147 | 0.9284 | 0.9098 | 1.6102 | |
| ZR75B | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11939.147 | 0.9397 | 0.9242 | 1.6102 | |
| ZR75B | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11939.147 | 0.9925 | 0.9906 | 1.6102 | |
| ZR75B | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11939.147 | 0.9946 | 0.9932 | 1.6102 | |
| ZR75B | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11939.147 | 0.9881 | 0.9852 | 1.6102 |