Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12608.147 | 0.9533 | 0.9279 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12608.147 | 0.9656 | 0.9469 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12608.147 | 0.9429 | 0.9117 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12608.147 | 0.9715 | 0.9560 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12608.147 | 0.9790 | 0.9676 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12608.147 | 0.9930 | 0.9892 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12608.147 | 0.9661 | 0.9477 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12608.147 | 0.9145 | 0.8672 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12608.147 | 0.5148 | 0.2005 | 1.3009 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10754.147 | 0.8439 | 0.7515 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10754.147 | 1.0125 | 1.0196 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10754.147 | 0.8676 | 0.7898 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10754.147 | 0.9495 | 0.9205 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10754.147 | 0.9539 | 0.9276 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10754.147 | 0.9472 | 0.9170 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10754.147 | 0.9978 | 0.9965 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10754.147 | 0.9888 | 0.9825 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10754.147 | 0.5442 | 0.2430 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11938.147 | 0.8554 | 0.5876 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11938.147 | 0.8852 | 0.6701 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11938.147 | 0.9182 | 0.7629 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11938.147 | 0.8553 | 0.5875 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11938.147 | 0.8953 | 0.6983 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11938.147 | 0.9018 | 0.7166 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11938.147 | 0.9057 | 0.7275 | 0.6765 |