Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9118.011 | 0.2371 | -0.4897 | 1.0538 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9118.011 | 0.2213 | -0.5219 | 1.0538 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9120.021 | 1.0727 | 1.2286 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9120.021 | 0.9726 | 0.9160 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9120.021 | 1.0362 | 1.1126 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9120.021 | 0.9945 | 0.9831 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9120.021 | 1.0333 | 1.1037 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9120.021 | 0.8985 | 0.6957 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9120.021 | 0.7832 | 0.3722 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9120.021 | 0.3149 | -0.6632 | 0.6486 | |
| 600MPE | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9120.021 | 0.0829 | -0.9570 | 0.6486 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7793.011 | 1.0359 | 1.0625 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7793.011 | 0.9244 | 0.8674 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7793.011 | 0.9661 | 0.9406 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7793.011 | 0.9815 | 0.9676 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7793.011 | 0.9948 | 0.9910 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7793.011 | 0.5839 | 0.2504 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7793.011 | 0.2121 | -0.4835 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7793.011 | 0.0074 | -0.9724 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7793.011 | 0.0106 | -0.9621 | 1.1456 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9146.12 | 0.9356 | 0.8839 | 1.1135 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9146.12 | 0.9294 | 0.8727 | 1.1135 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9146.12 | 1.0715 | 1.1279 | 1.1135 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9146.12 | 0.8983 | 0.8163 | 1.1135 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9146.12 | 0.8876 | 0.7969 | 1.1135 |