Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 5898.093 | 0.9285 | 0.7979 | 0.6963 | |
| 600MPE | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 5898.093 | 0.9392 | 0.8277 | 0.6963 | |
| 600MPE | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 5898.093 | 0.8900 | 0.6917 | 0.6963 | |
| 600MPE | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 5898.093 | 0.0405 | -0.9800 | 0.6963 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 5900.093 | 1.0530 | 1.0453 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 5900.093 | 1.0352 | 1.0302 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 5900.093 | 1.0198 | 1.0171 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 5900.093 | 1.0444 | 1.0380 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 5900.093 | 1.0496 | 1.0424 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 5900.093 | 0.9970 | 0.9974 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 5900.093 | 1.0171 | 1.0148 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 5900.093 | 0.6731 | 0.6848 | 2.3084 | |
| AU565 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 5900.093 | 0.1656 | -0.0822 | 2.3084 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 5904.1 | 1.0256 | 1.0381 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 5904.1 | 0.9226 | 0.8830 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 5904.1 | 1.0108 | 1.0162 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 5904.1 | 0.9245 | 0.8859 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 5904.1 | 0.9580 | 0.9368 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 5904.1 | 0.9794 | 0.9691 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 5904.1 | 1.0451 | 1.0671 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 5904.1 | 0.8805 | 0.8184 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 5904.1 | 0.0258 | -0.8704 | 1.3369 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 10385.093 | 1.0518 | 1.1732 | 0.6082 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 10385.093 | 1.0638 | 1.2141 | 0.6082 | |
| BT-20 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 10385.093 | 1.0472 | 1.1576 | 0.6082 |