Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10472.087 | 1.0476 | 1.1742 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10472.087 | 0.9061 | 0.6751 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10472.087 | 0.8142 | 0.3824 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10472.087 | 0.5193 | -0.3838 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10472.087 | 0.2313 | -0.8559 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 10472.087 | 0.0439 | -0.9927 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 10472.087 | 0.0112 | -0.9994 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 10472.087 | 0.0071 | -0.9997 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 10472.087 | 0.0041 | -0.9999 | 0.5566 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10643.087 | 1.0371 | 1.1151 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10643.087 | 0.9544 | 0.8618 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10643.087 | 0.7935 | 0.4023 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10643.087 | 0.4573 | -0.3980 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10643.087 | 0.2096 | -0.8182 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 10643.087 | 0.0345 | -0.9886 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 10643.087 | 0.0093 | -0.9985 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 10643.087 | 0.0052 | -0.9994 | 0.6516 | |
| MDA-MB-361 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 10643.087 | 0.0006 | -1.0000 | 0.6516 | |
| MDA-MB-415 | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7511.086 | 1.0129 | 1.0207 | 1.2442 | |
| MDA-MB-415 | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7511.086 | 0.9065 | 0.8483 | 1.2442 | |
| MDA-MB-415 | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7511.086 | 0.9411 | 0.9047 | 1.2442 | |
| MDA-MB-415 | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7511.086 | 0.7991 | 0.6701 | 1.2442 | |
| MDA-MB-415 | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7511.086 | 0.6178 | 0.3582 | 1.2442 | |
| MDA-MB-415 | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 7511.086 | 0.3723 | -0.0961 | 1.2442 | |
| MDA-MB-415 | HR+ | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 7511.086 | 0.1019 | -0.6808 | 1.2442 |