Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9146.12 | 0.5109 | 0.0942 | 1.1135 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9146.12 | 0.1629 | -0.6081 | 1.1135 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9146.12 | 0.0047 | -0.9837 | 1.1135 | |
| AU565 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9146.12 | 0.0057 | -0.9808 | 1.1135 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9157.021 | 1.0390 | 1.0770 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9157.021 | 0.9936 | 0.9874 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9157.021 | 0.9951 | 0.9904 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9157.021 | 0.9196 | 0.8408 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9157.021 | 0.9464 | 0.8940 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9157.021 | 0.9196 | 0.8410 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9157.021 | 0.6228 | 0.2521 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9157.021 | 0.4946 | -0.0030 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9157.021 | 0.0457 | -0.9054 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9158.12 | 0.8640 | 0.6314 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9158.12 | 1.0262 | 1.0734 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9158.12 | 0.9517 | 0.8666 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9158.12 | 0.8330 | 0.5504 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9158.12 | 1.0044 | 1.0124 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9158.12 | 0.8777 | 0.6677 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9158.12 | 0.8528 | 0.6019 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9158.12 | 0.4918 | -0.2561 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9158.12 | 0.0133 | -0.9952 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9163.011 | 1.0437 | 1.1411 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9163.011 | 1.0324 | 1.1045 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9163.011 | 1.0096 | 1.0309 | 0.6266 |