Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	10002.021	0.9997	0.9991	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	10002.021	1.0167	1.0465	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	10002.021	1.0368	1.1031	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	10002.021	0.9080	0.7490	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	10002.021	0.8339	0.5538	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	10002.021	0.7326	0.2978	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	10002.021	0.1876	-0.8047	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	126	uM	10002.021	0.0992	-0.9194	0.7195
184A1	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	10002.021	0.0207	-0.9908	0.7195
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	9095.119	1.0797	1.1291	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	9095.119	0.9797	0.9668	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	9095.119	1.0748	1.1211	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	9095.119	0.9017	0.8382	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	9095.119	0.7032	0.5007	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	9095.119	0.6539	0.4144	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	9095.119	0.4845	0.1076	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	126	uM	9095.119	0.0433	-0.8453	1.2263
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	9095.119	0.0113	-0.9485	1.2263
600MPE	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	9118.011	1.0662	1.1254	1.0538
600MPE	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	9118.011	1.0132	1.0250	1.0538
600MPE	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	9118.011	1.0289	1.0548	1.0538
600MPE	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	9118.011	0.9901	0.9812	1.0538
600MPE	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	9118.011	0.9599	0.9239	1.0538
600MPE	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	9118.011	0.8212	0.6591	1.0538
600MPE	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	9118.011	0.6629	0.3540	1.0538

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)