Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12365.147 | 1.2053 | 1.2140 | 1.8376 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12365.147 | 0.9542 | 0.9496 | 1.8376 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12365.147 | 0.9202 | 0.9115 | 1.8376 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12365.147 | 0.8952 | 0.8831 | 1.8376 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12365.147 | 1.2827 | 1.2902 | 1.8376 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12365.147 | 1.0625 | 1.0671 | 1.8376 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12365.147 | 0.0285 | -0.7116 | 1.8376 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10997.147 | 0.9232 | 0.8873 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10997.147 | 0.9493 | 0.9259 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10997.147 | 0.9647 | 0.9485 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10997.147 | 0.9671 | 0.9520 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10997.147 | 0.9755 | 0.9644 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10997.147 | 0.9741 | 0.9623 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10997.147 | 1.0167 | 1.0241 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10997.147 | 0.9614 | 0.9437 | 1.3792 | |
| MCF7 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10997.147 | 0.1754 | -0.4339 | 1.3792 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10998.147 | 0.9346 | 0.8483 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10998.147 | 0.9373 | 0.8546 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10998.147 | 0.9699 | 0.9299 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10998.147 | 0.9723 | 0.9356 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10998.147 | 0.9783 | 0.9493 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10998.147 | 0.9764 | 0.9451 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10998.147 | 1.0816 | 1.1915 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10998.147 | 0.9188 | 0.8118 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10998.147 | 0.7501 | 0.4300 | 0.8573 |