Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10695.147 | 0.9622 | 0.9498 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10695.147 | 0.9572 | 0.9431 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10695.147 | 1.0015 | 1.0020 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10695.147 | 0.9599 | 0.9466 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10695.147 | 0.8273 | 0.7647 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10695.147 | 0.4241 | 0.1349 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10695.147 | 0.0137 | -0.8822 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11852.147 | 0.9464 | 0.9292 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11852.147 | 1.0055 | 1.0072 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11852.147 | 0.9358 | 0.9150 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11852.147 | 0.9282 | 0.9049 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11852.147 | 1.0012 | 1.0016 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11852.147 | 0.8627 | 0.8158 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11852.147 | 0.7797 | 0.6995 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11852.147 | 0.4386 | 0.1663 | 1.5284 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11852.147 | 0.0370 | -0.7689 | 1.5284 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10939.147 | 0.9656 | 0.9597 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10939.147 | 1.0109 | 1.0127 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10939.147 | 0.9557 | 0.9480 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10939.147 | 0.9460 | 0.9365 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10939.147 | 0.9461 | 0.9365 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10939.147 | 0.9652 | 0.9592 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10939.147 | 0.9740 | 0.9696 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10939.147 | 0.8060 | 0.7642 | 1.7195 | |
| T47D | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10939.147 | 0.3682 | 0.1187 | 1.7195 |