Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12269.147 | 1.0475 | 1.1119 | 0.8519 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12269.147 | 0.9893 | 0.9749 | 0.8519 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12269.147 | 0.8766 | 0.7135 | 0.8519 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12269.147 | 0.4509 | -0.2148 | 0.8519 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12269.147 | 0.1817 | -0.7298 | 0.8519 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12098.147 | 0.9312 | 0.8838 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12098.147 | 0.8668 | 0.7736 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12098.147 | 0.9008 | 0.8320 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12098.147 | 0.8347 | 0.7184 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12098.147 | 0.8833 | 0.8020 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12098.147 | 0.9510 | 0.9173 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12098.147 | 0.9297 | 0.8811 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12098.147 | 1.0306 | 1.0512 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12098.147 | 0.2109 | -0.4591 | 1.1904 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11058.147 | 0.9549 | 0.9567 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11058.147 | 0.9043 | 0.9068 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11058.147 | 0.9427 | 0.9448 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11058.147 | 0.9780 | 0.9790 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11058.147 | 0.9570 | 0.9587 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11058.147 | 0.9209 | 0.9233 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11058.147 | 0.8506 | 0.8522 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11058.147 | 0.4452 | 0.3624 | 2.1077 | |
| SUM229PE | TNBC | - | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11058.147 | 0.1710 | -0.1349 | 2.1077 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10695.147 | 0.9868 | 0.9825 | 1.5141 | |
| SUM52PE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10695.147 | 1.0814 | 1.1060 | 1.5141 |