Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11056.147 | 1.0222 | 1.0158 | 2.7832 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11056.147 | 0.9075 | 0.9315 | 2.7832 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11056.147 | 0.6535 | 0.7165 | 2.7832 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11056.147 | 0.3474 | 0.3680 | 2.7832 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11056.147 | 0.0018 | -0.7954 | 2.7832 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12254.147 | 0.9775 | 0.9684 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12254.147 | 1.1051 | 1.1446 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12254.147 | 1.0465 | 1.0645 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12254.147 | 1.0794 | 1.1096 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12254.147 | 1.0372 | 1.0517 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12254.147 | 0.9773 | 0.9682 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12254.147 | 0.8847 | 0.8360 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12254.147 | 0.6247 | 0.4398 | 1.4316 | |
| MCF 10F | NM | - | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12254.147 | 0.0113 | -0.9129 | 1.4316 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10817.147 | 0.9445 | 0.9255 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10817.147 | 0.9872 | 0.9829 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10817.147 | 0.9722 | 0.9629 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10817.147 | 1.0315 | 1.0417 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10817.147 | 0.9891 | 0.9855 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10817.147 | 0.9897 | 0.9863 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10817.147 | 0.9538 | 0.9381 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10817.147 | 0.6169 | 0.4507 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10817.147 | 0.0295 | -0.8077 | 1.5041 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12365.147 | 1.2722 | 1.2800 | 1.8376 | |
| MCF12A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12365.147 | 1.2513 | 1.2595 | 1.8376 |