Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12291.147 | 0.9844 | 0.9481 | 0.5980 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12291.147 | 0.8427 | 0.5022 | 0.5980 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12291.147 | 0.3932 | -0.5802 | 0.5980 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10696.147 | 0.9252 | 0.6988 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10696.147 | 0.9150 | 0.6596 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10696.147 | 0.9514 | 0.8014 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10696.147 | 0.9178 | 0.6704 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10696.147 | 0.9622 | 0.8447 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10696.147 | 0.9740 | 0.8925 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10696.147 | 1.0125 | 1.0530 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10696.147 | 0.9680 | 0.8682 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10696.147 | 0.5035 | -0.5263 | 0.4763 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11855.147 | 0.8862 | 0.6192 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11855.147 | 0.8786 | 0.5950 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11855.147 | 0.9757 | 0.9158 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11855.147 | 0.9176 | 0.7207 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11855.147 | 0.9356 | 0.7802 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11855.147 | 0.9341 | 0.7752 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11855.147 | 0.9851 | 0.9483 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11855.147 | 0.9082 | 0.6899 | 0.5719 | |
| BT-483 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11855.147 | 0.5546 | -0.2866 | 0.5719 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12305.147 | 0.9921 | 0.9945 | 2.8865 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12305.147 | 1.0129 | 1.0089 | 2.8865 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12305.147 | 1.0850 | 1.0573 | 2.8865 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12305.147 | 0.9647 | 0.9753 | 2.8865 |