Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10816.147 | 1.1326 | 1.3730 | 0.7283 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10816.147 | 1.0530 | 1.1470 | 0.7283 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10816.147 | 0.1404 | -0.8650 | 0.7283 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12319.147 | 0.8906 | 0.8127 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12319.147 | 0.8735 | 0.7831 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12319.147 | 1.1192 | 1.2006 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12319.147 | 0.7562 | 0.5776 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12319.147 | 0.8337 | 0.7139 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12319.147 | 0.9005 | 0.8298 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12319.147 | 0.9937 | 0.9894 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12319.147 | 0.8476 | 0.7381 | 1.1783 | |
| LY2 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12319.147 | 0.0700 | -0.7907 | 1.1783 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12580.147 | 1.0110 | 1.0098 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12580.147 | 1.0029 | 1.0026 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12580.147 | 1.0083 | 1.0074 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12580.147 | 0.9845 | 0.9861 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12580.147 | 1.0274 | 1.0243 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12580.147 | 1.0521 | 1.0460 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12580.147 | 1.0516 | 1.0455 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12580.147 | 0.6536 | 0.6536 | 2.2358 | |
| MB 157 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12580.147 | 0.2197 | 0.0154 | 2.2358 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11056.147 | 0.9912 | 0.9937 | 2.7832 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11056.147 | 1.0733 | 1.0515 | 2.7832 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11056.147 | 1.0218 | 1.0155 | 2.7832 | |
| MCF 10A | NM | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11056.147 | 1.0229 | 1.0164 | 2.7832 |