Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10642.147 | 1.0651 | 1.2009 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10642.147 | 0.8088 | 0.4495 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10818.147 | 1.0074 | 1.0289 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10818.147 | 0.9304 | 0.7380 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10818.147 | 0.9879 | 0.9531 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10818.147 | 0.9432 | 0.7846 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10818.147 | 0.9632 | 0.8592 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10818.147 | 0.9700 | 0.8849 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10818.147 | 0.9647 | 0.8650 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10818.147 | 1.0098 | 1.0384 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10818.147 | 0.6134 | -0.2276 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12126.147 | 0.9095 | 0.7512 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12126.147 | 0.8991 | 0.7232 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12126.147 | 0.9279 | 0.8009 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12126.147 | 0.8788 | 0.6688 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12126.147 | 0.9216 | 0.7840 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12126.147 | 0.9014 | 0.7294 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12126.147 | 0.9314 | 0.8105 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12126.147 | 0.9329 | 0.8147 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12126.147 | 0.5160 | -0.2083 | 0.7140 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10643.147 | 0.9904 | 0.9700 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10643.147 | 1.0206 | 1.0652 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10643.147 | 0.9800 | 0.9373 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10643.147 | 1.0249 | 1.0789 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10643.147 | 1.0463 | 1.1479 | 0.6347 |