Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10643.147 | 1.0188 | 1.0595 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10643.147 | 1.0642 | 1.2060 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10643.147 | 1.0370 | 1.1178 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10643.147 | 0.5989 | -0.1083 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10999.147 | 0.9534 | 0.8993 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10999.147 | 0.9890 | 0.9762 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10999.147 | 0.9669 | 0.9284 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10999.147 | 0.9930 | 0.9849 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10999.147 | 0.9932 | 0.9853 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10999.147 | 0.9691 | 0.9332 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10999.147 | 1.0939 | 1.2040 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10999.147 | 0.9366 | 0.8632 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10999.147 | 0.2276 | -0.5970 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12379.147 | 1.1688 | 2.2603 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12379.147 | 1.2087 | 2.6220 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12379.147 | 1.0946 | 1.6545 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12379.147 | 1.0149 | 1.0951 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12379.147 | 0.9579 | 0.7479 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12379.147 | 0.8578 | 0.2368 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12379.147 | 1.1423 | 2.0341 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12379.147 | 1.1008 | 1.7022 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12379.147 | 0.0201 | -1.0000 | 0.3192 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10938.147 | 0.6304 | 0.2011 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10938.147 | 0.9099 | 0.8019 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10938.147 | 0.9908 | 0.9796 | 0.9050 |