Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7530.086 | 0.6489 | 0.6436 | 2.2038 | |
| SUM149PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7530.086 | 0.5185 | 0.4845 | 2.2038 | |
| SUM149PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 7530.086 | 0.3399 | 0.2256 | 2.2038 | |
| SUM149PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 7530.086 | 0.2105 | -0.0137 | 2.2038 | |
| SUM149PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 7530.086 | 0.0437 | -0.5167 | 2.2038 | |
| SUM149PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 7530.086 | 0.0209 | -0.6542 | 2.2038 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7531.086 | 1.0497 | 1.0295 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7531.086 | 0.9718 | 0.9828 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7531.086 | 0.8695 | 0.9173 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7531.086 | 0.5558 | 0.6748 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7531.086 | 0.2178 | 0.2621 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 7531.086 | 0.1108 | 0.0290 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 7531.086 | 0.1112 | 0.0301 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 7531.086 | 0.1108 | 0.0290 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 7531.086 | 0.0964 | -0.0133 | 3.3103 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10520.087 | 1.5358 | 1.4009 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10520.087 | 1.4504 | 1.3431 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10520.087 | 1.3871 | 1.2990 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10520.087 | 1.2405 | 1.1922 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10520.087 | 0.5269 | 0.5224 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 10520.087 | 0.2088 | 0.0265 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 10520.087 | 0.1320 | -0.1557 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 10520.087 | 0.1604 | -0.0825 | 2.3483 | |
| SUM159PT | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 10520.087 | 0.1284 | -0.1654 | 2.3483 | |
| SUM225CWN | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10579.087 | 0.9885 | 0.9760 | 0.9622 |