Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12084.147 | 1.0187 | 1.0343 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12084.147 | 0.9407 | 0.8907 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12084.147 | 0.9613 | 0.9288 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12084.147 | 1.0047 | 1.0086 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12084.147 | 1.0634 | 1.1161 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12084.147 | 0.9980 | 0.9963 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12084.147 | 1.1054 | 1.1928 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12084.147 | 0.8760 | 0.7709 | 1.0888 | |
| HCC1395 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12084.147 | 0.0443 | -0.8857 | 1.0888 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12001.147 | 0.9288 | 0.7679 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12001.147 | 0.9303 | 0.7727 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12001.147 | 0.9873 | 0.9578 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12001.147 | 0.8578 | 0.5481 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12001.147 | 0.9185 | 0.7353 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12001.147 | 0.9397 | 0.8026 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12001.147 | 0.9252 | 0.7566 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12001.147 | 0.8964 | 0.6662 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12001.147 | 0.6621 | 0.0047 | 0.5989 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10693.147 | 0.9498 | 0.8873 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10693.147 | 0.9974 | 0.9942 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10693.147 | 0.9818 | 0.9590 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10693.147 | 0.9830 | 0.9618 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10693.147 | 1.0229 | 1.0516 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10693.147 | 0.9355 | 0.8554 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10693.147 | 0.9670 | 0.9258 | 0.8879 |