Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11058.152 | 0.9690 | 0.9700 | 2.0809 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11058.152 | 1.0241 | 1.0230 | 2.0809 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11058.152 | 0.9345 | 0.9360 | 2.0809 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11058.152 | 1.0531 | 1.0504 | 2.0809 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11058.152 | 0.1885 | -0.1032 | 2.0809 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11058.152 | 0.0121 | -0.7599 | 2.0809 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 167 | uM | 11058.152 | 0.0084 | -0.7994 | 2.0809 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10695.152 | 1.0140 | 1.0223 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10695.152 | 0.9578 | 0.9322 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10695.152 | 1.1040 | 1.1648 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10695.152 | 0.9767 | 0.9626 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10695.152 | 1.0077 | 1.0124 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10695.152 | 0.9167 | 0.8656 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10695.152 | 0.1930 | -0.4640 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10695.152 | 0.0152 | -0.9299 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10695.152 | 0.0144 | -0.9330 | 1.2495 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11852.159 | 0.9601 | 0.9395 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11852.159 | 1.0246 | 1.0371 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11852.159 | 0.9965 | 0.9948 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11852.159 | 1.0645 | 1.0967 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11852.159 | 0.9241 | 0.8843 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11852.159 | 0.8345 | 0.7447 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11852.159 | 0.1984 | -0.4100 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11852.159 | 0.0134 | -0.9228 | 1.3247 | |
| SUM52PE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 11852.159 | 0.0095 | -0.9407 | 1.3247 |