Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12269.152 | 0.7074 | 0.3490 | 0.8791 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12269.152 | 0.5065 | -0.0775 | 0.8791 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12269.152 | 0.0085 | -0.9911 | 0.8791 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12269.152 | 0.0113 | -0.9878 | 0.8791 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12269.152 | 0.0088 | -0.9909 | 0.8791 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10579.14 | 1.0684 | 1.1473 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10579.14 | 0.9796 | 0.9561 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10579.14 | 1.0138 | 1.0296 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10579.14 | 1.0067 | 1.0145 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10579.14 | 1.0146 | 1.0314 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10579.14 | 0.9043 | 0.7950 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10579.14 | 0.2598 | -0.5302 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10579.14 | 0.0089 | -0.9874 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10579.14 | 0.0054 | -0.9927 | 0.9303 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12098.159 | 1.0078 | 1.0151 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12098.159 | 1.1103 | 1.2147 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12098.159 | 1.0035 | 1.0068 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12098.159 | 1.1064 | 1.2071 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12098.159 | 0.9103 | 0.8250 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12098.159 | 0.8907 | 0.7866 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12098.159 | 0.2852 | -0.4112 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12098.159 | 0.0067 | -0.9847 | 1.0261 | |
| SUM225CWN | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 12098.159 | 0.0070 | -0.9841 | 1.0261 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11058.152 | 0.9773 | 0.9780 | 2.0809 | |
| SUM229PE | TNBC | - | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11058.152 | 1.0653 | 1.0617 | 2.0809 |