Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 5897.086 | 1.0109 | 1.0170 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 5897.086 | 0.9632 | 0.9424 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 5897.086 | 0.8244 | 0.7203 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 5897.086 | 0.6152 | 0.3689 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 5897.086 | 0.3526 | -0.1133 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 0.267 | uM | 5897.086 | 0.3186 | -0.1808 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 1.33 | uM | 5897.086 | 0.3633 | -0.0924 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 6.67 | uM | 5897.086 | 0.1952 | -0.4412 | 1.2814 | |
| 184B5 | NM | Basal | Omipalisib | PI3K | PI3K | 33.3 | uM | 5897.086 | 0.1035 | -0.6593 | 1.2814 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 5898.086 | 1.0013 | 1.0044 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 5898.086 | 0.9242 | 0.7500 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 5898.086 | 0.8719 | 0.5855 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 5898.086 | 0.8226 | 0.4369 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 5898.086 | 0.6133 | -0.1264 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 5898.086 | 0.3778 | -0.6155 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 5898.086 | 0.2367 | -0.8258 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 5898.086 | 0.1648 | -0.9057 | 0.5904 | |
| 600MPE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 5898.086 | 0.1504 | -0.9192 | 0.5904 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 5900.086 | 1.0220 | 1.0202 | 2.1682 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 5900.086 | 0.9289 | 0.9331 | 2.1682 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 5900.086 | 0.7467 | 0.7479 | 2.1682 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 5900.086 | 0.5492 | 0.5170 | 2.1682 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 5900.086 | 0.3829 | 0.2845 | 2.1682 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 5900.086 | 0.3348 | 0.2074 | 2.1682 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 5900.086 | 0.3276 | 0.1954 | 2.1682 |