Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 5900.086 | 0.2111 | -0.0240 | 2.1682 | |
| AU565 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 5900.086 | 0.1991 | -0.0499 | 2.1682 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 5904.087 | 1.0475 | 1.0756 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 5904.087 | 0.9168 | 0.8658 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 5904.087 | 0.9339 | 0.8936 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 5904.087 | 0.7671 | 0.6178 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 5904.087 | 0.5136 | 0.1739 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 5904.087 | 0.2624 | -0.3138 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 5904.087 | 0.2127 | -0.4200 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 6.67 | uM | 5904.087 | 0.1610 | -0.5357 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 33.3 | uM | 5904.087 | 0.0795 | -0.7359 | 1.2506 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10385.087 | 1.0213 | 1.0470 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10385.087 | 0.9546 | 0.9001 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10385.087 | 0.9446 | 0.8782 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10385.087 | 0.9586 | 0.9089 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10385.087 | 0.7120 | 0.3755 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 10385.087 | 0.3771 | -0.3172 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 10385.087 | 0.2627 | -0.5416 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 6.67 | uM | 10385.087 | 0.2000 | -0.6606 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 33.3 | uM | 10385.087 | 0.0891 | -0.8607 | 0.9074 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10581.087 | 0.9787 | 0.9610 | 1.0948 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10581.087 | 0.8804 | 0.7803 | 1.0948 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10581.087 | 0.8818 | 0.7829 | 1.0948 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10581.087 | 0.8301 | 0.6872 | 1.0948 | |
| BT-20 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10581.087 | 0.5608 | 0.1792 | 1.0948 |