Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Nelfinavir | 0.0000853 | uM | 13091.174 | 0.9669 | 0.9172 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 0.000427 | uM | 13091.174 | 0.9550 | 0.8876 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 0.00213 | uM | 13091.174 | 0.9662 | 0.9155 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 0.0107 | uM | 13091.174 | 0.9750 | 0.9375 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 0.0533 | uM | 13091.174 | 0.9987 | 0.9967 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 0.267 | uM | 13091.174 | 0.9510 | 0.8778 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 1.33 | uM | 13091.174 | 0.9373 | 0.8439 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 6.67 | uM | 13091.174 | 0.8604 | 0.6561 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Nelfinavir | 33.3 | uM | 13091.174 | 0.1002 | -0.8885 | 0.7967 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 0.0000853 | uM | 13030.174 | 1.0054 | 1.0125 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 0.000427 | uM | 13030.174 | 0.9677 | 0.9252 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 0.00213 | uM | 13030.174 | 0.9487 | 0.8813 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 0.0107 | uM | 13030.174 | 0.9585 | 0.9040 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 0.0533 | uM | 13030.174 | 0.9699 | 0.9304 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 0.267 | uM | 13030.174 | 1.0123 | 1.0287 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 1.33 | uM | 13030.174 | 1.0102 | 1.0238 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 6.67 | uM | 13030.174 | 0.9727 | 0.9367 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Nelfinavir | 33.3 | uM | 13030.174 | 1.0274 | 1.0639 | 0.8615 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 13579.174 | 0.9898 | 0.9746 | 0.8018 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 13579.174 | 0.9709 | 0.9276 | 0.8018 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 13579.174 | 0.9743 | 0.9361 | 0.8018 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 13579.174 | 0.9765 | 0.9416 | 0.8018 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 13579.174 | 0.9927 | 0.9818 | 0.8018 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 13579.174 | 0.9910 | 0.9775 | 0.8018 | |||
| BT-20 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 13579.174 | 0.9644 | 0.9116 | 0.8018 |