Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.00427 | uM | 10644.135 | 0.9333 | 0.7545 | 0.5273 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.0213 | uM | 10644.135 | 1.0178 | 1.0680 | 0.5273 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.107 | uM | 10644.135 | 1.0299 | 1.1148 | 0.5273 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.533 | uM | 10644.135 | 1.0547 | 1.2127 | 0.5273 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 2.67 | uM | 10644.135 | 0.7048 | 0.0303 | 0.5273 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 13.3 | uM | 10644.135 | 0.3768 | -0.6858 | 0.5273 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 66.7 | uM | 10644.135 | 0.1700 | -0.9306 | 0.5273 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.000171 | uM | 10874.148 | 0.9824 | 0.9497 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.000853 | uM | 10874.148 | 1.0052 | 1.0150 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.00427 | uM | 10874.148 | 1.0083 | 1.0237 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.0213 | uM | 10874.148 | 0.9173 | 0.7671 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.107 | uM | 10874.148 | 0.7793 | 0.3986 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.533 | uM | 10874.148 | 1.0360 | 1.1040 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 2.67 | uM | 10874.148 | 1.0661 | 1.1923 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 13.3 | uM | 10874.148 | 0.9765 | 0.9329 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 66.7 | uM | 10874.148 | 1.0730 | 1.2128 | 0.6972 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.000171 | uM | 12220.135 | 0.8813 | 0.6498 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.000853 | uM | 12220.135 | 0.8649 | 0.6033 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.00427 | uM | 12220.135 | 0.9359 | 0.8079 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.0213 | uM | 12220.135 | 0.8968 | 0.6942 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.107 | uM | 12220.135 | 0.9845 | 0.9529 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 0.533 | uM | 12220.135 | 0.9753 | 0.9252 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 2.67 | uM | 12220.135 | 0.4305 | -0.4461 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 13.3 | uM | 12220.135 | 0.1588 | -0.8787 | 0.6564 | |
| MX1 | Unknown | Unknown | Pevonedistat | NAE1 | NAE1 | 66.7 | uM | 12220.135 | 0.1399 | -0.9001 | 0.6564 |