Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
184B5
NM
Basal
Nelfinavir
0.00213
uM
12979.174
0.9351 0.9162 1.5680
184B5
NM
Basal
Nelfinavir
0.0107
uM
12979.174
1.1044 1.1307 1.5680
184B5
NM
Basal
Nelfinavir
0.0533
uM
12979.174
1.1707 1.2115 1.5680
184B5
NM
Basal
Nelfinavir
0.267
uM
12979.174
1.0987 1.1238 1.5680
184B5
NM
Basal
Nelfinavir
1.33
uM
12979.174
0.9779 0.9716 1.5680
184B5
NM
Basal
Nelfinavir
6.67
uM
12979.174
0.4979 0.2819 1.5680
184B5
NM
Basal
Nelfinavir
33.3
uM
12979.174
0.0397 -0.7445 1.5680
21MT-1
HER2amp
-
Nelfinavir
0.0000853
uM
13719.174
0.9842 0.9613 0.8124
21MT-1
HER2amp
-
Nelfinavir
0.000427
uM
13719.174
0.9754 0.9396 0.8124
21MT-1
HER2amp
-
Nelfinavir
0.00213
uM
13719.174
0.9827 0.9576 0.8124
21MT-1
HER2amp
-
Nelfinavir
0.0107
uM
13719.174
0.9900 0.9753 0.8124
21MT-1
HER2amp
-
Nelfinavir
0.0533
uM
13719.174
0.9894 0.9740 0.8124
21MT-1
HER2amp
-
Nelfinavir
0.267
uM
13719.174
0.9788 0.9479 0.8124
21MT-1
HER2amp
-
Nelfinavir
1.33
uM
13719.174
0.9804 0.9518 0.8124
21MT-1
HER2amp
-
Nelfinavir
6.67
uM
13719.174
0.9565 0.8934 0.8124
21MT-1
HER2amp
-
Nelfinavir
33.3
uM
13719.174
0.0489 -0.9513 0.8124
21NT
HER2amp
-
Nelfinavir
0.0000853
uM
13575.174
0.9813 0.9763 1.5845
21NT
HER2amp
-
Nelfinavir
0.000427
uM
13575.174
0.9718 0.9642 1.5845
21NT
HER2amp
-
Nelfinavir
0.00213
uM
13575.174
0.9539 0.9413 1.5845
21NT
HER2amp
-
Nelfinavir
0.0107
uM
13575.174
0.9962 0.9952 1.5845
21NT
HER2amp
-
Nelfinavir
0.0533
uM
13575.174
0.9863 0.9827 1.5845
21NT
HER2amp
-
Nelfinavir
0.267
uM
13575.174
0.9831 0.9786 1.5845
21NT
HER2amp
-
Nelfinavir
1.33
uM
13575.174
0.9806 0.9754 1.5845
21NT
HER2amp
-
Nelfinavir
6.67
uM
13575.174
0.9885 0.9855 1.5845
21NT
HER2amp
-
Nelfinavir
33.3
uM
13575.174
0.2300 -0.2090 1.5845