Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12580.17 | 0.9152 | 0.9133 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12580.17 | 0.0708 | -0.4680 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12580.17 | 0.0708 | -0.4680 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12580.17 | 0.0183 | -0.7297 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12580.17 | 0.0183 | -0.7297 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12580.17 | 0.0190 | -0.7246 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12580.17 | 0.0190 | -0.7246 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12580.17 | 0.0163 | -0.7447 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12580.17 | 0.0163 | -0.7447 | 1.9993 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11056.145 | 1.1004 | 1.0685 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11056.145 | 1.1004 | 1.0685 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11056.145 | 1.0412 | 1.0287 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11056.145 | 1.0412 | 1.0287 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11056.145 | 1.0605 | 1.0418 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11056.145 | 1.0605 | 1.0418 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11056.145 | 0.9976 | 0.9983 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11056.145 | 0.9976 | 0.9983 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11056.145 | 0.1314 | -0.0215 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11056.145 | 0.1314 | -0.0215 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11056.145 | 0.0133 | -0.5639 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11056.145 | 0.0133 | -0.5639 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11056.145 | 0.0074 | -0.6442 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11056.145 | 0.0074 | -0.6442 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11056.145 | 0.0114 | -0.5859 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11056.145 | 0.0114 | -0.5859 | 2.8383 |