Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Nilotinib | ABL | nRTK | 40 | uM | 12509.17 | 0.8807 | 0.8260 | 1.3955 | |
| 184A1 | NM | Basal | Nilotinib | ABL | nRTK | 200 | uM | 12509.17 | 0.9381 | 0.9104 | 1.3955 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 0.000512 | uM | 12566.17 | 1.0026 | 1.0035 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 0.00256 | uM | 12566.17 | 0.9796 | 0.9720 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 0.0128 | uM | 12566.17 | 0.9920 | 0.9890 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 0.064 | uM | 12566.17 | 0.9827 | 0.9763 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 0.32 | uM | 12566.17 | 0.9589 | 0.9436 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 1.6 | uM | 12566.17 | 0.9380 | 0.9145 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 8 | uM | 12566.17 | 0.9553 | 0.9386 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 40 | uM | 12566.17 | 0.9504 | 0.9318 | 1.4648 | |
| 184B5 | NM | Basal | Nilotinib | ABL | nRTK | 200 | uM | 12566.17 | 0.9436 | 0.9223 | 1.4648 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 0.000512 | uM | 12224.145 | 1.0393 | 1.0807 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 0.00256 | uM | 12224.145 | 0.9747 | 0.9481 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 0.0128 | uM | 12224.145 | 1.0414 | 1.0850 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 0.064 | uM | 12224.145 | 1.0114 | 1.0233 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 0.32 | uM | 12224.145 | 1.0747 | 1.1536 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 1.6 | uM | 12224.145 | 1.0373 | 1.0766 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 8 | uM | 12224.145 | 1.0259 | 1.0533 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 40 | uM | 12224.145 | 0.9948 | 0.9894 | 0.9737 | |
| 600MPE | HR+ | Luminal | Nilotinib | ABL | nRTK | 200 | uM | 12224.145 | 1.0131 | 1.0269 | 0.9737 | |
| AU565 | HER2amp | Luminal | Nilotinib | ABL | nRTK | 0.000512 | uM | 10880.145 | 0.9743 | 0.9649 | 1.4751 | |
| AU565 | HER2amp | Luminal | Nilotinib | ABL | nRTK | 0.00256 | uM | 10880.145 | 0.9356 | 0.9117 | 1.4751 | |
| AU565 | HER2amp | Luminal | Nilotinib | ABL | nRTK | 0.0128 | uM | 10880.145 | 0.9856 | 0.9804 | 1.4751 | |
| AU565 | HER2amp | Luminal | Nilotinib | ABL | nRTK | 0.064 | uM | 10880.145 | 0.9880 | 0.9837 | 1.4751 | |
| AU565 | HER2amp | Luminal | Nilotinib | ABL | nRTK | 0.32 | uM | 10880.145 | 0.9225 | 0.8936 | 1.4751 |