Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF 10F
NM
-
Nelfinavir
0.0000853
uM
13750.174
0.9568 0.9392 1.4282
MCF 10F
NM
-
Nelfinavir
0.000427
uM
13750.174
0.9438 0.9206 1.4282
MCF 10F
NM
-
Nelfinavir
0.00213
uM
13750.174
0.9384 0.9129 1.4282
MCF 10F
NM
-
Nelfinavir
0.0107
uM
13750.174
0.9666 0.9530 1.4282
MCF 10F
NM
-
Nelfinavir
0.0533
uM
13750.174
0.9320 0.9037 1.4282
MCF 10F
NM
-
Nelfinavir
0.267
uM
13750.174
0.9507 0.9304 1.4282
MCF 10F
NM
-
Nelfinavir
1.33
uM
13750.174
0.9297 0.9005 1.4282
MCF 10F
NM
-
Nelfinavir
6.67
uM
13750.174
0.8208 0.7417 1.4282
MCF 10F
NM
-
Nelfinavir
33.3
uM
13750.174
0.0632 -0.7109 1.4282
MCF12A
NM
Basal B
Nelfinavir
0.0000853
uM
12949.174
0.9720 0.9704 1.9016
MCF12A
NM
Basal B
Nelfinavir
0.000427
uM
12949.174
0.9112 0.9045 1.9016
MCF12A
NM
Basal B
Nelfinavir
0.00213
uM
12949.174
0.9027 0.8952 1.9016
MCF12A
NM
Basal B
Nelfinavir
0.0107
uM
12949.174
1.0379 1.0395 1.9016
MCF12A
NM
Basal B
Nelfinavir
0.0533
uM
12949.174
1.0048 1.0051 1.9016
MCF12A
NM
Basal B
Nelfinavir
0.267
uM
12949.174
0.9441 0.9404 1.9016
MCF12A
NM
Basal B
Nelfinavir
1.33
uM
12949.174
0.8883 0.8792 1.9016
MCF12A
NM
Basal B
Nelfinavir
6.67
uM
12949.174
0.8842 0.8746 1.9016
MCF12A
NM
Basal B
Nelfinavir
33.3
uM
12949.174
0.5066 0.3987 1.9016
MCF7
HR+
Luminal
Nelfinavir
0.0000853
uM
12657.174
1.0016 1.0030 1.0776
MCF7
HR+
Luminal
Nelfinavir
0.000427
uM
12657.174
0.9773 0.9579 1.0776
MCF7
HR+
Luminal
Nelfinavir
0.00213
uM
12657.174
1.0033 1.0061 1.0776
MCF7
HR+
Luminal
Nelfinavir
0.0107
uM
12657.174
0.9681 0.9406 1.0776
MCF7
HR+
Luminal
Nelfinavir
0.0533
uM
12657.174
0.9913 0.9838 1.0776
MCF7
HR+
Luminal
Nelfinavir
0.267
uM
12657.174
0.9315 0.8725 1.0776
MCF7
HR+
Luminal
Nelfinavir
1.33
uM
12657.174
0.9754 0.9543 1.0776