Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7463.066 | 0.9667 | 0.8813 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7463.066 | 0.9557 | 0.8429 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7463.066 | 0.9169 | 0.7103 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7463.066 | 0.4542 | -0.5185 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7464.066 | 1.0043 | 1.0136 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7464.066 | 1.0298 | 1.0941 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7464.066 | 1.0295 | 1.0932 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7464.066 | 1.0354 | 1.1120 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7464.066 | 1.0785 | 1.2515 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7464.066 | 0.9906 | 0.9707 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7464.066 | 1.0358 | 1.1133 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7464.066 | 0.9314 | 0.7893 | 0.6384 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7464.066 | 0.4567 | -0.4141 | 0.6384 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7465.066 | 0.9362 | 0.8982 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7465.066 | 0.9027 | 0.8443 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7465.066 | 0.9564 | 0.9306 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7465.066 | 1.0021 | 1.0033 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7465.066 | 1.0590 | 1.0928 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7465.066 | 0.9553 | 0.9288 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7465.066 | 0.9276 | 0.8844 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7465.066 | 0.9170 | 0.8674 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7465.066 | 0.4061 | -0.0204 | 1.2627 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7466.066 | 1.0121 | 1.0257 | 0.9420 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7466.066 | 1.0273 | 1.0581 | 0.9420 | |
| HCC3153 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7466.066 | 1.0448 | 1.0952 | 0.9420 |