Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11056.145 | 0.0060 | -0.6701 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11056.145 | 0.0060 | -0.6701 | 2.8383 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14215.189 | 0.9385 | 0.9627 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14215.189 | 0.9385 | 0.9627 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14215.189 | 0.8964 | 0.9361 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14215.189 | 0.8964 | 0.9361 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14215.189 | 0.9538 | 0.9721 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14215.189 | 0.9538 | 0.9721 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14215.189 | 0.8903 | 0.9321 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14215.189 | 0.8903 | 0.9321 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14215.189 | 0.2448 | 0.3165 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14215.189 | 0.2448 | 0.3165 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14215.189 | 0.0721 | -0.0845 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14215.189 | 0.0721 | -0.0845 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14215.189 | 0.0065 | -0.5529 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14215.189 | 0.0065 | -0.5529 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14215.189 | 0.0899 | -0.0224 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14215.189 | 0.0899 | -0.0224 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14215.189 | 0.9379 | 0.9623 | 3.3654 | |
| MCF 10A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14215.189 | 0.9379 | 0.9623 | 3.3654 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12254.145 | 1.0787 | 1.0866 | 1.7869 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12254.145 | 1.0787 | 1.0866 | 1.7869 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12254.145 | 1.1037 | 1.1135 | 1.7869 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12254.145 | 1.1037 | 1.1135 | 1.7869 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12254.145 | 1.0402 | 1.0446 | 1.7869 |