Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14131.189 | 0.0805 | -0.7427 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14131.189 | 0.0189 | -0.9209 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14131.189 | 0.0189 | -0.9209 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14131.189 | 0.0145 | -0.9362 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14131.189 | 0.0145 | -0.9362 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14131.189 | 0.9724 | 0.9549 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14131.189 | 0.9724 | 0.9549 | 1.2288 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10578.145 | 0.9413 | 0.9291 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10578.145 | 0.9413 | 0.9291 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10578.145 | 0.9203 | 0.9033 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10578.145 | 0.9203 | 0.9033 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10578.145 | 0.9340 | 0.9202 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10578.145 | 0.9340 | 0.9202 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10578.145 | 0.9524 | 0.9426 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10578.145 | 0.9524 | 0.9426 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10578.145 | 0.9088 | 0.8891 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10578.145 | 0.9088 | 0.8891 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10578.145 | 0.2520 | -0.1209 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10578.145 | 0.2520 | -0.1209 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10578.145 | 0.0011 | -0.9651 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10578.145 | 0.0011 | -0.9651 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10578.145 | 0.0079 | -0.8886 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10578.145 | 0.0079 | -0.8886 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10578.145 | 0.0005 | -0.9775 | 1.6766 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10578.145 | 0.0005 | -0.9775 | 1.6766 |