Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14134.189 | 1.1136 | 1.0796 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14134.189 | 1.1136 | 1.0796 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14134.189 | 1.0078 | 1.0057 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14134.189 | 1.0078 | 1.0057 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14134.189 | 1.1573 | 1.1088 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14134.189 | 1.1573 | 1.1088 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14134.189 | 1.0167 | 1.0120 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14134.189 | 1.0167 | 1.0120 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14134.189 | 0.7214 | 0.7766 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14134.189 | 0.7214 | 0.7766 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14134.189 | 0.1950 | 0.1054 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14134.189 | 0.1950 | 0.1054 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14134.189 | 0.0413 | -0.3706 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14134.189 | 0.0413 | -0.3706 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14134.189 | 1.2720 | 1.1824 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14134.189 | 1.2720 | 1.1824 | 2.7572 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12580.17 | 0.9961 | 0.9961 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12580.17 | 0.9961 | 0.9961 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12580.17 | 1.0219 | 1.0218 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12580.17 | 1.0219 | 1.0218 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12580.17 | 1.0301 | 1.0299 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12580.17 | 1.0301 | 1.0299 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12580.17 | 0.9953 | 0.9953 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12580.17 | 0.9953 | 0.9953 | 1.9993 | |
| MB 157 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12580.17 | 0.9152 | 0.9133 | 1.9993 |